Biochemical ‘fossil’ shows how life may have emerged without phosphate

One major mystery about life’s origin is how phosphate became an essential building block of genetic and metabolic machinery in cells, given its poor accessibility on early Earth. Researchers have used systems biology approaches to tackle this long-standing conundrum, providing compelling, data-driven evidence that primitive life forms may not have relied on phosphate at all. Instead, a few simple, abundant molecules could have supported the emergence of a sulfur-based, phosphate-free metabolism.
Geology News — ScienceDaily